Information AgeMedicine & Health Smallpox eradicated 1980Turning point The first human disease wiped out by deliberate effort. ▲ MattersSaveShareTrace roots Longest chain: The Big Bang → First stars ignite → Supernovae seed heavy elements → The Sun forms → Earth forms → First oceans → First life → Photosynthesis evolves → Great Oxidation Event → Complex cells (eukaryotes) → Multicellular life → First animals → Cambrian Explosion → First vertebrates → Jawed fish → Fish walk onto land → The amniotic egg → The Great Dying → Dinosaurs appear → Asteroid ends the dinosaurs → Early primates → Apes split from monkeys → Human line splits from chimpanzees → Walking upright → First stone tools → Genus Homo appears → Homo erectus → Control of fire → Habitual fire and cooking → Homo sapiens appears → Complex language → Natufian villages → Oldest known bread → Agriculture begins → Irrigation → Uruk and the first cities → Cylinder seals → Writing (cuneiform) → Babylonian mathematics → Babylonian astronomical diaries → Thales and natural philosophy → Trial and death of Socrates → Plato's Academy → Aristotle's Lyceum → Alexander's conquests → Alexandria founded → Library of Alexandria → House of Wisdom → Al-Khwarizmi and algebra → Fibonacci's Liber Abaci → Bills of exchange → Medici Bank → Double-entry bookkeeping → Muscovy Company → English East India Company → Seven Years' War → American Revolution → Declaration of Independence → French Revolution → Revolutions of 1848 → German unification → World War I → Treaty of Versailles → Great Depression → Nazis take power → World War II → United Nations → Smallpox eradicated Community notesLoading notes… Learn more ranked by votesDocumentwho.intCommemorating smallpox eradication (World Health Organization) ↗Editor's pickDocumentcdc.govHistory of smallpox (CDC) ↗Editor's pickBookWilliam H. FoegeHouse on Fire ↗Editor's pickVideoSearch on YouTubeeradication of smallpox ↗Editor's pick